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The authors conclude that chronic methamphetamine-treated rats assign greater motivational values to large rewards. But the dopamine blockers had minimal impact on rats who gambled with out the flashing lights and sound cues. The rats, who gambled for sugary treats, normally learn how to avoid the dangerous options. Within the methamphetamine-treated rats, the researchers found evidence of neural activation within the insular cortex, nucleus accumbens, and striatum associated with altered resolution making. Further, after receiving the massive reward, the methamphetamine-treated rats exhibited “win-keep” habits, choosing the H-H arm extra continuously in subsequent trials than did the management rats, despite the likelier destructive outcome of the quinine pellet. Additionally, when the methamphetamine-handled rats obtained the quinine pellet within the L-L arm, they switched to the H-H arm on the next attempt much more frequently than the control rats. They additional explored the neurological modifications precipitated by methamphetamine treatment by subjecting the rats to c-Fos immunohistochemistry, reporting a lot of outcomes

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